Journal of Clinical and Translational Hepatology

Journal of Clinical and Translational Hepatology

Monday, 03 / 08 / 2021

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Hispanic Patients with Primary Biliary Cholangitis Have Decreased Access to Care Compared to Non-Hispanics

Atoosa Rabiee*,1, Nathalie A Pena Polanco2Aymara Fernandez De La Vara3 and Cynthia Levy2

1  Department of Gastroenterology and Hepatology, VA Medical Center, Washington DC, USA
2  Divison of Digestive Health and Liver Diseases Department of Medicine University of Miami Miller School of Medicine USA
3  Department of Medicine, Jackson Memorial Hospital, University of Miami, Miami, FL, USA
*Correspondence to: Atoosa Rabiee, Department of Gastroenterology and Hepatology, VA Medical Center, 50 Irving St NW, Washington DC 20422, USA. Tel: +1-202-745-8456, E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Journal of Clinical and Translational Hepatology 2020;8(4):391-396 DOI: 10.14218/JCTH.2020.00006
Received: January 28, 2020 Accepted: September 18, 2020 Published online: October 29, 2020


Background and Aims: Hispanic patients with primary biliary cholangitis (PBC) have reduced rates of biochemical response to ursodeoxycholic acid (UDCA) and increased risk of disease progression compared to non-Hispanic patients. In this study, we sought to identify differences in demographics, comorbidities, environmental risk factors and socioeconomic status between Hispanic and non-Hispanic patients with PBC.

Methods: In a case control study, we analyzed data from Hispanic (n=37 females and 1 male) and non-Hispanic (n=54 females and 4 males) patients with PBC seen at the University of Miami/Jackson Memorial Hospital from January 1998 through January 2013. Data were obtained by filling out a questionnaire either via phone call, mail, or e-mail. Odds ratios were calculated to measure the association between exposure and outcomes.

Results: Baseline demographics, environmental risk factors and comorbidities were similar between Hispanic and non-Hispanic patients with PBC. Hispanic patients were less likely to be married and fewer Hispanics had education beyond high school level compared to non-Hispanics. Sixty four percent of Hispanic patients had a household income of less than $50000, compared to 19.5% of non-Hispanics. Fewer Hispanic patients with PBC had health insurance coverage compared to non-Hispanics (86.5% vs. 98.1%; odds ratio: 0.1, 95% confidence interval: 0-0.9).

Conclusions: Differences in disease severity and response to therapy observed in prior studies could not be explained by environmental exposures. In addition to genetic variation, socioeconomic discrepancies (access to care) may further explain these differences.


Primary biliary cholangitis, Ethnicity, Health disparity

Journal of Clinical and Translational Hepatology 2020 vol. 8, 391-396  [ Html  ] [ PDF Full-text ]

© The Authors 2020. This article is published under the terms of the Creative Commons Attribution-Noncommercial License (CC BY-NC 4.0), which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license.


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