Articles

A Review on the Management of Biliary Complications after Orthotopic Liver Transplantation

REVIEW ARTICLE

A Review on the Management of Biliary Complications after Orthotopic Liver Transplantation

Brian T. Moy and John W. Birk*

Department of Medicine, Division of Gastroenterology-Hepatology, University of Connecticut Health Center, Farmington, CT, USA
*Correspondence to: John W. Birk, Department of Medicine, Division of Gastroenterology-Hepatology, University of Connecticut Health Center, Farmington, CT 06030, USA. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Journal of Clinical and Translational Hepatology 2019;7(1):61-71 DOI: 10.14218/JCTH.2018.00028
Received: April 18, 2018 Accepted: October 29, 2018 Published online: December 3, 2018

Abstract
Orthotopic liver transplantation is the definitive treatment for end-stage liver disease and hepatocellular carcinomas. Biliary complications are the most common complications seen after transplantation, with an incidence of 10–25%. These complications are seen both in deceased donor liver transplant and living donor liver transplant. Endoscopic treatment of biliary complications with endoscopic retrograde cholangiopancreatography (commonly known as ERCP) has become a mainstay in the management post-transplantation. The success rate has reached 80% in an experienced endoscopist’s hands. If unsuccessful with ERCP, percutaneous transhepatic cholangiography can be an alternative therapy. Early recognition and treatment has been shown to improve morbidity and mortality in post-liver transplant patients. The focus of this review will be a learned discussion on the types, diagnosis, and treatment of biliary complications post-orthotopic liver transplantation.

Keywords
Biliary tract complication, Orthotropic liver transplantation, Stricture, Bile leak

 

 

 

Journal of Clinical and Translational Hepatology 2019 vol. 7, 61-71  [ Html ] [ PDF Full-text ]

 

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