Journal of Clinical and Translational Hepatology

Journal of Clinical and Translational Hepatology

Thursday, 05 / 13 / 2021

Articles

EDITORIAL

Recommendations and Clinical Guidance for Children with Metabolic-associated Fatty Liver Disease during the COVID-19 Pandemic

Yong-Hai Zhou#,1, Rafael S. Rios#,2, Kenneth I. Zheng#,2 and Ming-Hua Zheng*,2,3,4

1  Department of Pediatrics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
2  MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
3  Institute of Hepatology, Wenzhou Medical University, Wenzhou, Zhejiang, China
4  Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, Zhejiang, China
#  These authors contributed equally to this study.
*Correspondence to: Ming-Hua Zheng, MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, No. 2 Fuxue Lane, Wenzhou, Zhejiang 325000, China. Tel: +86-577-55579622, Fax: +86-577-55578522. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Journal of Clinical and Translational Hepatology 2021;9(1):1-2 DOI: 10.14218/JCTH.2020.00137
Received: November 28, 2020 Accepted: January 13, 2021 Published online: February 1, 2021

 

The outbreak of coronavirus disease-2019 (COVID-19), a new disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019 affected most countries in the world within just a few months. By March 11, 2020, the Director-General at the World Health Organization (WHO) declared that COVID-19 can be considered a pandemic, and as of January 11, 2021, there were over 88.8 million cases of COVID-19 worldwide and 1.9 million deaths reported by WHO. In order to prevent the further spread of this epidemic outbreak, measures such as social distancing, stay-at-home orders, and school closure were executed in many countries. However, these measures also greatly reduced the opportunities for physical activity among children. Based on past experience, there are indications that an increased rate of weight gain occurs during summer school vacation for overweight children. Therefore, it is reasonable to speculate that under the influence of the COVID-19 epidemic, long-term school closures may significantly increase the risk of weight gain in obese children. For children with metabolic-associated fatty liver disease (MAFLD), formerly known as nonalcoholic fatty liver disease, weight reduction through lifestyle changes (caloric restriction and physical activity) is considered as the first step in reversing disease progression, which makes managing MAFLD in children quite difficult during the ongoing COVID-19 pandemic. In addition, several studies found a significant correlation between a higher risk of severe illness from COVID-19 and metabolic disorders (e.g. diabetes, obesity, MAFLD).

 

 

Journal of Clinical and Translational Hepatology 2021 vol. 9, 1-2  [ Html  ] [ PDF Full-text ]

© The Author(s) 2021. This article is published under the terms of the Creative Commons Attribution-Noncommercial License (CC BY-NC 4.0), which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license.

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