Journal of Clinical and Translational Hepatology

Journal of Clinical and Translational Hepatology

Thursday, 12 / 09 / 2021

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Abstract

REVIEW ARTICLE

Alcohol and Metabolic-associated Fatty Liver Disease

Fu-Rong Sun and Bing-Yuan Wang*

Department of Elderly Gastroenterology, The First Hospital of China Medical University, Shenyang, Liaoning, China
*Correspondence to:Bing-Yuan Wang, Department of Elderly Gastroenterology, The First Hospital of China Medical University, Shenyang, Liaoning, China. ORCID:https://orcid.org/0000-0002-4233-6093 . Tel: + 86-24-8328-3764, E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Journal of Clinical and Translational Hepatology 2021;9(5):719-730 DOI: 10.14218/JCTH.2021.00173
Received:May 10, 2021 Accepted:June 17, 2021 Published online:July 19, 2021

Abstract

The diagnosis of metabolic-associated fatty liver disease is based on the detection of liver steatosis together with the presence of metabolic dysfunction. According to this new definition, the diagnosis of metabolic-associated fatty liver disease is independent of the amount of alcohol consumed. Actually, alcohol and its metabolites have various effects on metabolic-associated abnormalities during the process of alcohol metabolism. Studies have shown improved metabolic function in light to moderate alcohol drinkers. There are several studies focusing on the role of light to moderate alcohol intake on metabolic dysfunction. However, the results from studies are diverse, and the conclusions are often controversial. This review systematically discusses the effects of alcohol consumption, focusing on light to moderate alcohol consumption, obesity, lipid and glucose metabolism, and blood pressure.

Keywords

Alcohol, Metabolic-associated fatty liver disease, Obesity, Insulin resistance, Hypertension

Journal of Clinical and Translational Hepatology 2021 vol. 9, 719-730  [ Html  ] [ PDF Full-text ]

© 2021 Authors. This is an Open Access article distributed under the terms of the  Creative Commons Attribution-Noncommercial 4.0 License(CC BY-NC 4.0), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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