Original Article

Metabolic Liver Diseases

RASAL2 Deficiency Attenuates Hepatic Steatosis by Promoting Hepatic VLDL Secretion via the AKT/TET1/MTTP Axis Hao Ding, Jiang-Hong Yu, Ge Ge, Yan-Yun Ma, Jiu-Cun Wang, Jun Zhang, Jie Liu Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00042

Osteopontin Promotes Macrophage M1 Polarization by Activation of the JAK1/STAT1/HMGB1 Signaling Pathway in Nonalcoholic Fatty Liver Disease Zhihao Xu, Feiyang Xi, Xinxin Deng, Yuqi Ni, Changqin Pu, Dan Wang, Weiming Lou, Xufang Zeng, Ning Su, Chen Chen, Ziqiang Zeng, Libin Deng, Meixiu Jiang Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00474

Hepatic Alarmins and Mitochondrial Dysfunction under Residual Hyperlipidemic Stress Lead to Irreversible NAFLD Luminita Ivan, Elena Uyy, Viorel I. Suica, Raluca M. Boteanu, Aurel Cerveanu-Hogas, Rune Hansen, Felicia Antohe Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00128

Infectious Hepatitis

CD55 Variant Associated with Pegylated-interferon α Therapy Response in HBeAg-positive Chronic Hepatitis B Patients Jiaxuan Chen, Shuang Lou, Haitao Chen, Bin Zhou, Jian Sun, Jinlin Hou, De-Ke Jiang Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00057

Reduction in Intrahepatic cccDNA and Integration of HBV in Chronic Hepatitis B Patients with a Functional Cure Weiqiang Gan, Na Gao, Lin Gu, Zhishuo Mo, Xiuqing Pang, Ziying Lei, Zhiliang Gao Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00177

DILI, Autoimmune, and Cholestatic Diseases

Peptidomic Analysis Reveals that Novel Peptide LDP2 Protects Against Hepatic Ischemia/Reperfusion Injury Qun Bao, Zhengxin Wang, Sheng Cheng, Jin Zhang, Qiuli Liu, Yunpeng Zhang, Daqing Cheng, Xirong Guo, Xingyun Wang, Bo Han, Peng Sun Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00094

Prognostic Factors Related to In-hospital Death in Children with Biliary Atresia: Analysis of a Nationwide Inpatient Database Yu Shi, Yi-Zhou Jiang, Guang-Peng Zhou, Ying Shi, Lan-Xia Gan, Yuan-Yuan Kong, Hai-Bo Wang, Zhi-Jun Zhu, Li-Ying Sun Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00456

Time of Liver Function Abnormal Identification on Prediction of the Risk of Anti-tuberculosis-induced Liver Injury Deliang Huang, Jinghan Peng, Lin Lei, Yuanyuan Chen, Zhibing Zhu, Qingxian Cai, Yongcong Deng, Jun Chen Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00077

Liver Failure, Cirrhosis and Portal Hypertension

An-Luo-Hua-Xian Pill Improves the Regression of Liver Fibrosis in Chronic Hepatitis B Patients Treated with Entecavir Yi-Qi Liu, Chi Zhang, Jia-Wen Li, Li-Hua Cao, Zhan-Qing Zhang, Wei-Feng Zhao, Qing-Hua Shang, Da-Zhi Zhang, An-Lin Ma, Qing Xie, Hong-Lian Gui, Guo Zhang, Ying-Xia Liu, Jia Shang, Shi-Bin Xie, Jun Li, Xu-Qing Zhang, Zhi-Qiang Zou, Yu-Ping Chen, Zong Zhang, Ming-Xiang Zhang, Jun Cheng, Fu-Chun Zhang, Li-Hua Huang, Jia-Bin Li, Qing-Hua Meng, Hai-Bin Yu, Yu-Qiang Mi, Yan-Zhong Peng, Zhi-Jin Wang, Li-Ming Chen, Fan-Ping Meng, Wan-Hua Ren, Lang Bai, Yi-Lan Zeng, Rong Fan, Xian-Zhi Lou, Wei-Feng Liang, Hui Liu, Hui Zhuang, Hong Zhao, Gui-Qiang Wang Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00091

MRI/PAI Dual-modal Imaging-guided Precise Tracking of Bone Marrow-derived Mesenchymal Stem Cells Labeled with Nanoparticles for Treating Liver Cirrhosis Feng-Yong Liu, Ming Shi, Xin Li, Hong-Jun Yuan, Xiao-Mei Tian, Yi-Mao Xia, Min Zhou, Fu-Sheng Wang Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00580

Establishment of a Rat Model of Liver Venous Deprivation: Simultaneous Portal and Hepatic Vein Ligation Yuefeng Zhang, Xiaoqin He, Peng Ma, Liangkun Xiong, Wenhui Bai, Gaoshuo Zhang, Yangtao Xu, Wei Song, Kaihuan Yu Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00032

Efficacy and Economic Evaluation of Nonbiological Artificial Liver Therapy in Acute-on-chronic Hepatitis B Liver Failure Cichun Wu, Wenting Peng, Da Cheng, Huimin Gu, Fei Liu, Shifang Peng, Lei Fu Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00106

Hepatic and Biliary Neoplasia

RP11-40C6.2 Inactivates Hippo Signaling by Attenuating YAP1 Ubiquitylation in Hepatitis B Virus-associated Hepatocellular Carcinoma Han Zhuo, Chen Wu, Junwei Tang, Feihong Zhang, Zhenggang Xu, Dongwei Sun, Yue Teng, Zhongming Tan Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00584

Evaluation of GALAD Score in Diagnosis and Follow-up of Hepatocellular Carcinoma after Local Ablative Therapy Rasha Eletreby, Marwa Elsharkawy, Alaa Awad Taha, Mohamed Hassany, Amr Abdelazeem, Mohamed El-Kassas, Ahmed Soliman Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00013

New Staging Model for Radiation-based Hepatocellular Carcinoma Treatment: A National Multicenter Study Ting-Shi Su, Shi-Xiong Liang, Li-Qing Li, Qiu-Hua Liu, Xue-Zhang Duan, Jing Sun, Hai Zeng, Hai-Sheng Zhu, Jian-Xu Li, Xiao-Fei Zhu, Hong-Qing Zhuang, Ping Liang, Yong Huang Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00002

Evaluation of Preoperative Microvascular Invasion in Hepatocellular Carcinoma Through Multidimensional Parameter Combination Modeling Based on Gd-EOB-DTPA MRI Han-Dan Zhang, Xiao-Ming Li, Yu-Han Zhang, Fang Hu, Liang Tan, Fang Wang, Yang Jing, Da-Jing Guo, Yang Xu, Xian-Ling Hu, Chen Liu, Jian Wang Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00546

125I Radioactive Particles Drive Protective Autophagy in Hepatocellular Carcinoma by Upregulating ATG9B Yunhua Xiao, Jing Yuan, Chongshuang Yang, Junru Xiong, Liangyu Deng, Qinghua Liang, Chuang He, Liangshan Li, Fengtian He, Xuequan Huang Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00023

Overexpression of RBM34 Promotes Tumor Progression and Correlates with Poor Prognosis of Hepatocellular Carcinoma Wei Wang, Rui Zhang, Ning Feng, Longzhen Zhang, Nianli Liu Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00166

Review Article

Unraveling the Emerging Niche Role of Hepatic Stellate Cell-derived Exosomes in Liver Diseases Kun-Li Yin, Ming Li, Pei-Pei Song, Yu-Xin Duan, Wen-Tao Ye, Wei Tang, Norihiro Kokudo, Qiang Gao, Rui Liao Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00326

Intestinal Barrier Function in the Pathogenesis of Nonalcoholic Fatty Liver Disease Lu Liu, Minyue Yin, Jingwen Gao, Chenyan Yu, Jiaxi Lin, Airong Wu, Jinzhou Zhu, Chunfang Xu, Xiaolin Liu Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00089

Seronegative Autoimmune Hepatitis Sriya A. Bhumi, George Y. Wu Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00235

Comprehensive Approach to Assessment of Liver Viability During Normothermic Machine Perfusion Jiahao Li, Haoyang Lu, Jian Zhang, Yixuan Li, Qiang Zhao Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00130

Role of Transarterial Chemoembolization in the Treatment of Hepatocellular Carcinoma Bin-Yan Zhong, Zhi-Cheng Jin, Jian-Jian Chen, Hai-Dong Zhu, Xiao-Li Zhu Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00293

Combination Therapies for Advanced Biliary Tract Cancer Weifeng Zeng, Ruiqi Mao, Zhanguo Zhang, Xiaoping Chen Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00277

Nonalcoholic Fatty Liver Disease in Lean/Nonobese and Obese Individuals: A Comprehensive Review on Prevalence, Pathogenesis, Clinical Outcomes, and Treatment Ankoor H. Patel, Dhiraj Peddu, Sahil Amin, Mohamed I. Elsaid, Carlos D. Minacapelli, Toni-Marie Chandler, Carolyn Catalano, Vinod K. Rustgi Published online: April 28, 2023 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00204