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Online First Articles
The online first articles are peer reviewed, accepted, and are ready for publication, with copyediting, typesetting, proofreading and author review. They have not been assigned to a journal issue; an article will be removed from this page once it is published in a coming issue.

Articles published online first are citable. To cite an article on this page, please refer to the following example:

Yi SG, Sadhu AR, Jones SL, Turner K, Monsour H, Donahue K, et al. The Effect of Adrenal Replacement Therapy on Rates of Fungal Colonization and Mortality in Critically Ill Patients Awaiting Liver Transplantation. J Clin Transl Hepatol. Published online: Sep 15, 2013. doi: 10.14218/JCTH.2013.00007.

Original Article

Metabolic Liver Diseases

Mapping Metabolic Dysfunction-associated Steatotic Liver Disease Models of Care across 17 Middle East and North Africa Countries: Insights into Guidelines, Infrastructure, and Referral Systems

Mohamed El-Kassas, Khalid M. AlNaamani, Rofida Khalifa, Yusuf Yilmaz, Asma Labidi, Maen Almattooq, Faisal M. Sanai, Maisam W.I. Akroush Nabil Debzi, Mohammed A. Medhat, Imam Waked, Ali Tumi, Mohamed Elbadry, Mohammed Omer Mohammed, Ala I. Sharara, Ali El Houni, Mohamed Alsenbesy, Hisham El-Khayat, Mina Tharwat, Abdel-Naser Elzouki, Khalid A. Alswat, Zobair M. Younossi, on behalf of the Steatotic Liver Disease Study Foundation in Middle East and North Africa (SLMENA) Collaborators

Published online: September 1, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00286

Arctigenin Prevents Metabolic Dysfunction-associated Steatohepatitis by Inhibiting NLRP3/GSDMD-N Axis in Macrophages

Rui Xue, Lu Jiang, Qian-Ren Zhang, Qing-Jing Wang, Rui-Xu Yang, Tian-Yi Ren, Qin Pan, Jian-Gao Fan

Published online: August 25, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00141

Liver Failure, Cirrhosis and Portal Hypertension

Hepatosplenic Volumes and Portal Pressure Gradient Identify One-year Further Decompensation Risk Post-transjugular Intrahepatic Portosystemic Shunt

Xinyu Chen, Yicheng Lin, Kefeng Jia, Rong Lv, Jiajun Tian, Fenghui Li, Jun Li, Yiwen Zhang, Ning Wang, Zhongsong Gao, Weili Yin, Fang Wang, Ping Zhu, Chao Yang, Jiayin Wang, Tao Wang, Junqing Yan, Ying Liu, Qing Ye, Huiling Xiang

Published online: September 3, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00199

Clinical Characteristics and Outcomes of Portal Vein Thrombosis in Patients with Porto-sinusoidal Vascular Disease: A Cohort Study

Yanglan He, Hui Liu, Yanna Liu, Ying Han, Chunlei Fan, Yanjing Wu, Lingna Lyv, Xueying Liang, Huiguo Ding

Published online: August 27, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00093

Liver Injury, Autoimmune, and Cholestatic Diseases

Protective Effect of Mesaconate on Autoimmune Hepatitis via Suppression of Inflammatory Response and Oxidative Stress

Qian Zhang, Jiajun Wang, Yifan He, Kun Zhang, Wei Hong, Tao Han

Published online: July 18, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00112

Review Article

Research Progress on Leptin in Metabolic Dysfunction-associated Fatty Liver Disease

Jian-Li Wang, Yue Xiao, Ming-Long Li, Guo-Li Chen, Miao-Hang Cui, Jin-Long Liu

Published online: September 5, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00204

The Role of Hepatic SIRT1: From Metabolic Regulation to Immune Modulation and Multi-target Therapeutic Strategies

Houyan Zhang, Dongjie Wu, Qingjuan Wu, Yanxuan Wu, Ziwei Guo, Li Wang, Yi Wang, Qian Zeng, Liang Shi, Bin Shi, Gongchang Yu, Wenliang Lv

Published online: September 3, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00259

Autoimmune Hepatitis Associated with Other Autoimmune Diseases: A Critical Review

Danzhu Zhao, George Y. Wu

Published online: August 27, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00153

Portal Vein Thrombosis in Liver Cirrhosis: A Review of Risk Factors and Predictive Indicators

Zhicheng Yang, Yongle Zhao, Honglin Chen, Han Zhang, Maoting Tan, Xianliu Li, Lingling Tao, Hongyun Zhao

Published online: July 29, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00124

Consensus

Consensus on the Management of Liver Injury Associated with Targeted Drugs and Immune Checkpoint Inhibitors for Hepatocellular Carcinoma (Version 2024)

Suxian Zhao, Jie Li, Lingdi Liu, Sha Huang, Yanhang Gao, Mei Liu, Yu Chen, Lai Wei, Jidong Jia, Hong You, Zhongping Duan, Hui Zhuang, Jingfeng Liu, Xiaoyuan Xu, Yuemin Nan, Chinese Society of Hepatology, Chinese Medical Association

Published online: September 12, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00228

Mini Review

The Mechanisms behind Thrombocytopenia in Patients with Portal Hypertension and Chronic Liver Disease

Valeria M. Fernández-Garibay, Mariana M. Ramírez-Mejia, Guadalupe Ponciano-Rodriguez, Ran Wang, Xingshun Qi, Nahum Méndez-Sánchez

Published online: September 3, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00279

Research Letter

Impact of Alanine Transaminase Thresholds on Treatment Eligibility of Patients with Chronic Hepatitis B: A Cross-sectional Study of the China Registry of Hepatitis B

Hao Wang, Xiaoqian Xu, Shan Shan, Yuemin Nan, Xiaoyuan Xu, Hui Zhuang, Hong You, Jidong Jia, Yuanyuan Kong, China Registry of Hepatitis B (CR-HepB) Group

Published online: August 22, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00252

Development and Validation of a Novel Noninvasive Model to Predict Liver Fibrosis Staging in Untreated Patients with Chronic Hepatitis B

Jianhua Hu, Xiaoli Zhang, Zhibo Zhou, Fangfang Geng, Hongyu Jia, Linfeng Jin, Weixiang Zhong, Guodong Yu, Xue Wen, Hainv Gao, Yida Yang

Published online: July 7, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00175

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