Online First Articles
The online first articles are peer reviewed, accepted, and are ready for publication, with copyediting, typesetting, proofreading and author review. They have not been assigned to a journal issue; an article will be removed from this page once it is published in a coming issue.

Articles published online first are citable. To cite an article on this page, please refer to the following example:

Yi SG, Sadhu AR, Jones SL, Turner K, Monsour H, Donahue K, et al. The Effect of Adrenal Replacement Therapy on Rates of Fungal Colonization and Mortality in Critically Ill Patients Awaiting Liver Transplantation. J Clin Transl Hepatol. Published online: Sep 15, 2013. doi: 10.14218/JCTH.2013.00007.

Original Article

Metabolic Liver Diseases

Short-term Physical Activity Reduces Metabolic-associated Steatohepatitis by Promoting the Degradation of Branched-chain Amino Acids in Skeletal Muscle

Mingshu Gao, Jiaying Li, Yanan Zhang, Jiangtao Huang, Jiaqi Chen, Dawen Liao, Shengnan He, Qian Bi, Lele Ji, Yulu Du

Published online: May 30, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00072

Investigation of HO-1 Regulation of Liver Fibrosis Related to Nonalcoholic Fatty Liver Disease Through the SIRT1/TGF-ß/Smad3 Pathway

Mengjiao Sun, Xiaoqing Wu, Zhandong Lin, Congyue Zhang, Jiawei Cui, Yaoyao Mao, Yue Shi, Jiaming Zhang, Yuemin Nan

Published online: March 12, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00481

Intestinal Depletion of TM6SF2 Exacerbates High-fat Diet-induced Metabolic Dysfunction-associated Steatotic Liver Disease through the Gut-liver Axis

Li-Zhen Chen, Yu-Rong Wang, Zhen-Zhen Zhao, Shou-Lin Zhao, Cong-Cong Min, Yong-Ning Xin

Published online: March 12, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00407

Infectious Hepatitis

Global Trends and Cross-country Inequalities of Acute Hepatitis E in the Elderly, 1990–2021: A Comprehensive Analysis

Deliang Huang, Jinyan Jiang, Jinghan Peng, Zhibin Zhu, Yuanyuan Chen, Siyu Zhang, Huiyi Lai, Hong Yu, Qi Zhao, Yanna Wu, Yanping Chen, Jun Chen

Published online: May 30, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00101

The Gut Microbiota in Elderly Patients with Acute Hepatitis E Infection

Miaomiao Li, Meng Shi, Changyi Ji, Luyu Wang, Ze Xiang, Ying Wang, Hongtao Wang, Mengmeng Gu, Runing Ji, Jian Wu

Published online: May 26, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00111

Liver Failure, Cirrhosis and Portal Hypertension

Improved Discrimination and Predictive Ability of Novel Prognostic Scores for Long-term Mortality in Hospitalized Patients with Cirrhosis

Sipu Wang, Gaoyue Guo, Han Wang, Xuqian Zhang, Wanting Yang, Jie Yang, Liping Wu, Chao Sun

Published online: March 11, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00004

Hepatic and Biliary Neoplasia

CCNE1 Promotes the Progression of Hepatic Precancerous Lesion and the Malignant Phenotype of Hepatocellular Carcinoma

Kai Zhang, Xue Hu, Lichao Yao, Wenzhi Guo

Published online: April 28, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00428

Oleanolic Acid Restores Drug Sensitivity in Sorafenib-resistant Hepatocellular Carcinoma: Evidence from In Vitro and In Vivo Studies

Tongtong Li, Xuan Shen, Tao Zhang, Jiaheng Ren, Wang Wang, Didi Wang, Pengxia Zhang

Published online: April 18, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00369

Review Article

Epidemiology, Achievements, and Challenges in the Elimination of Hepatitis B in China

You Deng, Tongtong Meng, Hong You, Jidong Jia, Yu Wang

Published online: May 21, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00039

The Role of Novel Immunomodulators in the Treatment of Autoimmune Hepatitis

Jing Li, Huanhuan Wang, Jie Lin, Aili Wang, Shuiyin Miao, Huaie Liu

Published online: May 13, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00008

Molecular and Histological Profiles and Relevant Imaging Signatures of Intrahepatic Cholangiocarcinoma

Huizhen Huang, Feng Chen

Published online: April 30, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00410

Hot Topic Commentary

Ketamine Hepatotoxicity: An Underappreciated Cause of Liver Damage - Analysis by RUCAM

Bianca Thakkar, George Y. Wu

Published online: April 11, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00478

Research Letter

Characteristics of a Chinese Cohort of Patients with Chronic Hepatitis C Infection (2019–2023) and a Case Report of Resistance-associated Substitutions to Sofosbuvir-velpatasvir Treatment

Hao Xiong, Shaokun Pan, Chaohui Zhou, Hong Shi, Youhua Xie, Jinsheng Guo

Published online: April 10, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00033

Corrigendum

Corrigendum: Liver Characterization of a Cohort of Alpha-1 Antitrypsin Deficiency Patients with and without Lung Disease

Published online: May 14, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2024.00201C

Consensus

Chinese Expert Consensus for the Management of Thrombocytopenia in Cirrhosis

Xiaoyuan Xu, Yujuan Guan, Jinghang Xu, Song Yang, Yifan Han, Jidong Jia, Yuemin Nan, Lai Wei, Zhongping Duan, Hui Zhuang

Published online: April 24, 2025

[ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00105

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