Original Article

Liver Failure, Cirrhosis and Portal Hypertension

Inflammation and Mitochondrial Dysfunction in Cirrhotic Cardiomyopathy: Therapeutic Implications Yijie Ding, Chengfeng Huang, Guannan Yang, En Liu, Zhongxin Wang, Yong Su, Chaoliang Ge Published online: November 28, 2025 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00237

Global Prevalence, Temporal Trends, and Associated Mortality of Bacterial Infections in Patients with Liver Cirrhosis: A Meta-analysis Yu-Xin Tian, Bai-Yun Wu, Qi An, Yin-Ping Wu, Jing Zuo, Yee Hui Yeo, Yu-Chen Fan Published online: November 28, 2025 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00260

Hepatic and Biliary Neoplasia

IL1RA+ Myeloid-derived Suppressor Cells Activate Epithelial-mesenchymal Transition to Facilitate Lymphatic and Hepatic Metastasis in Pancreatic Ductal Carcinoma Huan Liu, Jian Zhang, Shengnan Lv, Xinyu Peng, Han Liu, Haijun Li, Feng Wei Published online: November 28, 2025 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00416

DysUFMylation of SREBP1 Promotes the Progression of Hepatocellular Carcinoma by Reprogramming Lipid Metabolism Xukang Gao, Zeping Han, Min Xu, Zhutao Wang, Guoqiang Sun, Hao Xiao, Dai Zhang, Shuangjian Qiu, Ning Ren, Chenhao Zhou, Yong Yi Published online: November 28, 2025 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00318

Review Article

Research Progress on Leptin in Metabolic Dysfunction-associated Fatty Liver Disease Jian-Li Wang, Yue Xiao, Ming-Long Li, Guo-Li Chen, Miao-Hang Cui, Jin-Long Liu Published online: November 28, 2025 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00204

The Role of Mitochondrial Complexes in Liver Diseases Hai An Published online: November 28, 2025 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00194

Mini Review

The Mechanisms behind Thrombocytopenia in Patients with Portal Hypertension and Chronic Liver Disease Valeria M. Fernández-Garibay, Mariana M. Ramírez-Mejia, Guadalupe Ponciano-Rodriguez, Ran Wang, Xingshun Qi, Nahum Méndez-Sánchez Published online: November 28, 2025 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00279

Consensus

Consensus on the Management of Liver Injury Associated with Targeted Drugs and Immune Checkpoint Inhibitors for Hepatocellular Carcinoma (Version 2024) Suxian Zhao, Jie Li, Lingdi Liu, Sha Huang, Yanhang Gao, Mei Liu, Yu Chen, Lai Wei, Jidong Jia, Hong You, Zhongping Duan, Hui Zhuang, Jingfeng Liu, Xiaoyuan Xu, Yuemin Nan, Chinese Society of Hepatology, Chinese Medical Association Published online: November 28, 2025 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00228

Research Letter

Immunoglobulin G4-related Autoimmune Hepatitis: Diagnosis and Treatment Fang Wei, Jiping Zhang, Xuan An Published online: November 28, 2025 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00288

Impact of Alanine Transaminase Thresholds on Treatment Eligibility of Patients with Chronic Hepatitis B: A Cross-sectional Study of the China Registry of Hepatitis B Hao Wang, Xiaoqian Xu, Shan Shan, Yuemin Nan, Xiaoyuan Xu, Hui Zhuang, Hong You, Jidong Jia, Yuanyuan Kong, China Registry of Hepatitis B (CR-HepB) Group Published online: November 28, 2025 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00252

Hot Topic Commentary

Intrahepatic Cholestasis of Pregnancy: A Hot Topic Commentary Bianca Thakkar, George Y. Wu Published online: November 28, 2025 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2025.00381