Editorial

Newcastle Disease Virus/HK84: Next Potential Star for Targeted Immunotherapy of Hepatocellular Carcinoma? Weiyi Huang, Wenjun Chang Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00553

Impaired Pulmonary Function as a Potential Contributor to Reduced Exercise Capacity Associated with MAFLD Derrick Michael Van Rooyen, Oyekoya Taiwo Ayonrinde Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2022.00103

Original Article

Metabolic Liver Diseases

Interaction of SAMM50-rs738491, PARVB-rs5764455 and PNPLA3-rs738409 Increases Susceptibility to Nonalcoholic Steatohepatitis Ke Xu, Kenneth I. Zheng, Pei-Wu Zhu, Wen-Yue Liu, Hong-Lei Ma, Gang Li, Liang-Jie Tang, Rafael S. Rios, Giovanni Targher, Christopher D. Byrne, Xiao-Dong Wang, Yong-Ping Chen, Ming-Hua Zheng Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00067

Metabolic Dysfunction-associated Fatty Liver Disease is Associated with Greater Impairment of Lung Function than Nonalcoholic Fatty Liver Disease Lei Miao, Li Yang, Li-Sha Guo, Qiang-Qiang Shi, Teng-Fei Zhou, Yang Chen, Huai Zhang, Hui Cai, Zhi-Wei Xu, Shuan-Ying Yang, Hai Lin, Zhe Cheng, Ming-Yang Zhu, Xu Nan, Shuai Huang, Ya-Wen Zheng, Giovanni Targher, Christopher D Byrne, Yu-Ping Li, Ming-Hua Zheng, Cheng-Shui Chen Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00306

Infectious Hepatitis

Risk Factors of Chronic Kidney Disease in Chronic Hepatitis B: A Hospital-based Case-control Study from China Yunqi Liu, Ximei Wang, Fuping Xu, Dengren Li, Huimin Yang, Nan Sun, Yu-Chen Fan, Xiangdong Yang Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00082

Gamma-glutamyl Transpeptidase to Platelet Ratio Predicts Liver Injury in Hepatitis B e Antigen-negative Chronic Hepatitis B Patients With Normal Alanine Aminotransferase Xiang-An Zhao, Jian Wang, Jie Wei, Jiacheng Liu, Guangmei Chen, Li Wang, Guiyang Wang, Juan Xia, Weihua Wu, Shengxia Yin, Xin Tong, Xiaomin Yan, Weimao Ding, Xiaoxing Xiang, Rui Huang, Chao Wu Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00151

Liver Failure, Cirrhosis and Portal Hypertension

Vibration-controlled Transient Elastography for Assessment of Liver Fibrosis at a USA Academic Medical Center Max Shen, Anna Lee, Jay H. Lefkowitch, Howard J. Worman Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00188

KRT17 Promotes the Activation of HSCs via EMT in Liver Fibrosis Jing Chen, Si-Jia Ge, Hai-Juan Feng, Shu-Zhen Wu, Ran Ji, Wei-Rong Huang, Wei Huang, Cui-Hua Lu Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00101

Hepatic and Biliary Neoplasia

Preoperative Assessment of Abdominal Adipose Tissue to Predict Microvascular Invasion in Small Hepatocellular Carcinoma Zongqian Wu, Hong Lu, Qiao Xie, Jie Cheng, Kuansheng Ma, Xiaofei Hu, Liang Tan, Huarong Zhang, Chen Liu, Xiaoming Li, Ping Cai Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00126

Irreversible Electroporation for Hepatocellular Carcinoma Abutting the Diaphragm: A Prospective Single-center Study Yangyang Ma, Zhixian Chen, Bing Liang, Rongrong Li, Jianyu Li, Zhonghai Li, Mao Lin, Lizhi Niu Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00019

A New Prognostic Model Covering All Stages of Intrahepatic Cholangiocarcinoma Shuang-Nan Zhou, Shan-Shan Lu, Da-Wei Ju, Ling-Xiang Yu, Xiao-Xiao Liang, Xiao Xiang, Suthat Liangpunsakul, Lewis R. Roberts, Yin-Ying Lu, Ning Zhang Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00099

A Nomogram-based Model to Predict Neoplastic Risk for Patients with Gallbladder Polyps Xudong Zhang, Jincheng Wang, Baoqiang Wu, Tao Li, Lei Jin, Yong Wu, Peng Gao, Zhen Zhang, Xihu Qin, Chunfu Zhu Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00078

A Molecular Hepatocellular Carcinoma Prognostic Score System Precisely Predicts Overall Survival of Hepatocellular Carcinoma Patients Jie Jia, Jing Tang Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00010

Oncolytic Activity of Wild-type Newcastle Disease Virus HK84 Against Hepatocellular Carcinoma Associated with Activation of Type I Interferon Signaling Liming Chen, Yongdong Niu, Jiating Sun, Hong Lin, Guoxi Liang, Min Xiao, Dongmei Shi, Jia Wang, Huachen Zhu, Yi Guan Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00284

Expression and Regulatory Network Analysis of Function of Small Nucleolar RNA Host Gene 4 in Hepatocellular Carcinoma Jing Cao, Cuicui Xiao, Christ-Jonathan Tsia Hin Fong, Jiao Gong, Danyang Li, Xiangyong Li, Yusheng Jie, Yutian Chong Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2020.00175

Prognostic Role and Potential Mechanisms of N6-methyladenosine-related Long Noncoding RNAs in Hepatocellular Carcinoma Tianxing Dai, Jing Li, Linsen Ye, Haoyuan Yu, Mingbin Deng, Wei Liu, Hua Li, Yang Yang, Guoying Wang Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00096

Review Article

Targeted Mitochondrial Delivery to Hepatocytes: A Review Brent D. Heineman, Xiaocong Liu, George Y. Wu Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00093

Metabolic-associated Fatty Liver Disease (MAFLD): A Multi-systemic Disease Beyond the Liver Eda Kaya, Yusuf Yilmaz Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00178

Coagulation and Endothelial Dysfunction Associated with NAFLD: Current Status and Therapeutic Implications Doris Ogresta, Anna Mrzljak, Maja Cigrovski Berkovic, Ines Bilic-Curcic, Sanja Stojsavljevic-Shapeski, Lucija Virovic-Jukic Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00268

Glutaminolysis-ammonia-urea Cycle Axis, Non-alcoholic Fatty Liver Disease Progression and Development of Novel Therapies Ángela Rojas, María Rosario García-Lozano, Antonio Gil-Gómez, Manuel Romero-Gómez, Javier Ampuero Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00247

Recent Progress and Future Direction for the Application of Multiomics Data in Clinical Liver Transplantation Zhengtao Liu, Jun Xu, Shuping Que, Lei Geng, Lin Zhou, Adil Mardinoglu, Shusen Zheng Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00219

Redefinition of Fatty Liver Disease from NAFLD to MAFLD through the Lens of Drug Development and Regulatory Science Yasser Fouad, Melissa Palmer, Minjun Chen, Arie Regev, Rajarshi Banerjee, Rob Myers, Robert Riccio, Richard Torstenson, Ramy Younes, Puneet S. Arora, Henrik Landgren, Morten A. Karsdal, Martin Blake, David A. Shapiro, Hans-Juergen Gruss, Muhammad Y. Sheikh, Dina Attia, Steven Bollipo, Alastair D. Smith, Bradley Freilich, Robert G. Gish, Detlef Schuppan Published online: April 28, 2022 [ Html ] [ PDF Full-text ] [ Citations ] Doi: 10.14218/JCTH.2021.00408