Journal of Clinical and Translational Hepatology

Journal of Clinical and Translational Hepatology

Saturday, 10 / 16 / 2021

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Table of Contents

Editorial

Can Weather Influence the Prevalence of Acute-on-chronic Liver Failure?
Matthew McMillin
Abstract ] [ Html ] [ PDF Full-text ] 285-286 Doi: 10.14218/JCTH.2019.00058

Original Article

Intrahepatic Cholangiocarcinoma and Thermal Ablation: Long-term Results of An Italian Retrospective Multicenter Study
Antonio Giorgio, Pietro Gatti, Luca Montesarchio, Bruno Santoro, Andrea Dell’Olio, Nicola Crucinio, Carmine Coppola, Ferdinando Scarano, Fabio De Biase, Emanuela Ciracì, Stefano Semeraro, Valentina Giorgio
Abstract ] [ Html ] [ PDF Full-text ] 287-292 Doi: 10.14218/JCTH.2019.00036

Alanine Aminotransferase as the First Test Parameter for Wilson’s Disease
Hisao Hayashi, Kazumasa Watanabe, Ayano Inui, Ayako Kato, Yasuaki Tatsumi, Akihiko Okumura, Tomoo Fujisawa, Koichi Kato
Abstract ] [ Html ] [ PDF Full-text ] 293-296 Doi: 10.14218/JCTH.2019.00042

Association of GCKR Gene Polymorphisms with the Risk of Nonalcoholic Fatty Liver Disease and Coronary Artery Disease in a Chinese Northern Han Population
Hui Gao, Shousheng Liu, Zhenzhen Zhao, Xinjuan Yu, Qun Liu, Yongning Xin, Shiying Xuan
Abstract ] [ Html ] [ PDF Full-text ] 297-303 Doi: 10.14218/JCTH.2019.00030

Minimal Hepatic Encephalopathy in Indians: Psychometric Hepatic Encephalopathy Score and Inhibitory Control Test for Diagnosis and Rifaximin or Lactulose for Its Reversal
Vinay B. Pawar, Ravindra G. Surude, Nikhil Sonthalia, Vinay Zanwar, Samit Jain, Qais Contractor, Pravin M. Rathi
Abstract ] [ Html ] [ PDF Full-text ] 304-312 Doi: 10.14218/JCTH.2017.00037

Liver Stiffness Measurement Can Reflect the Active Liver Necroinflammation in Population with Chronic Liver Disease: A Real-world Evidence Study
Leijie Wang, Mingyu Zhu, Lihua Cao, Mingjie Yao, Yiwei Lu, Xiajie Wen, Ying Zhang, Jing Ning, Huiling Long, Yueyong Zhu, Guoxin Hu, Shuangsuo Dang, Qingchun Fu, Liang Chen, Xinxin Zhang, Jingmin Zhao, Zhiliang Gao, Yuemin Nan, Fengmin Lu
Abstract ] [ Html ] [ PDF Full-text ] 313-321 Doi: 10.14218/JCTH.2019.00040

Baseline Characteristics and Treatment Patterns of the Patients Recruited to the China Registry of Hepatitis B
Shan Shan, Hong You, Junqi Niu, Jia Shang, Wen Xie, Yuexin Zhang, Xun Li, Hong Ren, Hong Tang, Huiguo Ding, Xihong Wang, Yuemin Nan, Xiaoguang Dou, Tao Han, Lingyi Zhang, Xiaoqing Liu, Cunliang Deng, Jilin Cheng, Xiaozhong Wang, Qing Xie, Shumei Lin, Yan Huang, Youqing Xu, Yong Xiong, Wu Li, Xuebing Yan, Hongxin Piao, Wenxiang Huang, Qinghua Lu, Weijin Gong, Shiping Li, Xiaoxuan Hu, Xiaolan Zhang, Shourong Liu, Yufang Li, Dongliang Yang, Hai Li, Caixia Yang, Mingliang Cheng, Liaoyun Zhang, Huanwei Zheng, Xinhua Luo, Feng Lin, Lei Wang, Guanghua Xu, Xiaoyuan Xu, Lai Wei, Jinlin Hou, Zhongping Duan, Hui Zhuang, Xizhong Yang, Yuanyuan Kong, Jidong Jia, for the CR-HepB study group, Beijing, China
Abstract ] [ Html ] [ PDF Full-text ] 322-328 Doi: 10.14218/JCTH.2019.00052

Outcomes and Toxicology of Herbal Drugs in Alcoholic Hepatitis – A Single Center Experience from India
Cyriac Abby Philips, Sasidharan Rajesh, Tom George, Rizwan Ahamed, Sandeep Kumbar, Philip Augustine
Abstract ] [ Html ] [ PDF Full-text ] 329-340 Doi: 10.14218/JCTH.2019.00043

The Association between Meteorological Factors and the Prevalence of Acute-on-chronic Liver Failure: A Population-based Study, 2007–2016
Su Lin, Lifen Han, Dongliang Li, Ting Wang, Zimu Wu, Haoyang Zhang, Zhansong Xiao, Yinlian Wu, Jiaofeng Huang, Mingfang Wang, Yueyong Zhu
Abstract ] [ Html ] [ PDF Full-text ] 341-345 Doi: 10.14218/JCTH.2019.00044

Review Article

Highlights for Dental Care as a Hepatitis C Risk Factor: A Review of Literature
Leon D. Averbukh, George Y. Wu
Abstract ] [ Html ] [ PDF Full-text ] 346-351 Doi: 10.14218/JCTH.2019.00023

The Direct Contribution of Astrocytes and Microglia to the Pathogenesis of Hepatic Encephalopathy
Victoria Jaeger, Sharon DeMorrow, Matthew McMillin
Abstract ] [ Html ] [ PDF Full-text ] 352-361 Doi: 10.14218/JCTH.2019.00025

Pathogenesis of Insulin Resistance and Atherogenic Dyslipidemia in Nonalcoholic Fatty Liver Disease
Daud H. Akhtar, Umair Iqbal, Luis Miguel Vazquez-Montesino, Brittany B. Dennis, Aijaz Ahmed
Abstract ] [ Html ] [ PDF Full-text ] 362-370 Doi: 10.14218/JCTH.2019.00028

Role of Granulocyte Colony-stimulating Factor Therapy in Cirrhosis, ‘Inside Any Deep Asking Is the Answering’
Cyriac Abby Philips, Philip Augustine, Rizwan Ahamed, Sasidharan Rajesh, Tom George, Gopakumar C. Valiathan, Solomon K. John
Abstract ] [ Html ] [ PDF Full-text ] 371-383 Doi: 10.14218/JCTH.2019.00034

Intensive Care Management of Acute Liver Failure: Considerations While Awaiting Liver Transplantation
Anil Seetharam
Abstract ] [ Html ] [ PDF Full-text ] 384-391 Doi: 10.14218/JCTH.2019.00032

Reviewer Acknowledgement

2019 Reviewer Acknowledgement
Editorial Office of Journal of Clinical and Translational Hepatology
Abstract ] [ Html ] [ PDF Full-text ] 392-393 Doi: 10.14218/JCTH.2019.000RA

REVIEWER ACKNOWLEDGEMENT

2019 Reviewer Acknowledgement

Editorial Office of Journal of Clinical and Translational Hepatology

Journal of Clinical and Translational Hepatology 2019;7(4):392-393 DOI: 10.14218/JCTH.2019.000RA
Published online: December 20, 2019

We thank the following reviewers for their contribution and support in 2019.

Mai Ali Abd el Meguid

Egypt

Mohamed Abdallah Al Hajj Abdallah

United States

Sherief Abd-Elsalam

Egypt

Anant Agarwalla

United States

Avin Aggarwal

United States

Kawtar Alkhalloufi

United States

Ahmed M. Alkhunaizi

Saudi Arabia

Khaled Amer

Egypt

Masahiro Arai

Japan

Leon Averbukh

United States

Timothy A. Bach

United States

Gyorgy Baffy

United States

Adriana de Los Anteles Barrios

Guatemala

Roopjeet Bath

United States

Ines Bilic-Curcic

CROATIA

Thomas Graham Bird

United Kingdom

John W Birk

United States

Peter Buch

United States

Chalermrat Bunchorntavakul

Thailand

Ozge Telci Caklili

Turkey

Wenqing (Wendy) Cao

United States

Vincenzo Cardinale

Italy

Guido Carpino

Italy

Ryan Chadha

United States

Naichaya Chamroonkul

Thailand

Jason Pik Eu Chang

Singapore

Phunchai Charatcharoenwitthaya

Thailand

Limin Chen

Canada

Yongpeng Chen

China

José Artur Chies

Brazil

Ashok Choudhury

India

Alessandro Csermely

Italy

Jessica Dahmus

United States

Victor David W

United States

Giovan Giuseppe Di Costanzo

Italy

Iliana B Doycheva

United States

Xingrong Du

United States

Atanu Kumar Dutta

India

Mohamed A. El-Guindi

Egypt

Gülsüm Ozlem Elpek

Turkey

Saleh Elwir

United States

Yu-Chen Fan

China

Jian-Gao Fan

China

Myriam Farah

Canada

Artin Galoosian

United States

Yanhang Gao

China

Antonio Giorgio

Italy

Amit Goel

India

George Boon-Bee Goh

Singapore

Humberto C Gonzalez

United States

Kazuhiko Hayashi

Japan

Noha Helal

Egypt

Jing Jing

China

Sandeep Kumar Karn

China

Ahyoung Kim

United States

John Koskinas

Greece

Karen Krok

United States

Pramod Kumar

India

Ewa Kurys-Denis

Poland

Chaoshuang Lin

China

Cheng-Hai Liu

China

Xiaocong Liu

United States

Shousheng Liu

China

Joyce A. Lloyd

United States

Lungen Lu

China

Mojtaba mafi

Iran (Islamic Republic of)

Sunil K Malonia

United States

Alessandro Mantovani

Italy

Qing Mao

China

Rosa Maria Martin-Mateos

Spain

Yong-Ping Mu

China

Seyedehsan Navabi

United States

Paul Naylor

United States

Bolin Niu

United States

James Park

United States

Jie Peng

China

Cyriac Abby Philips

India

Madhumita Premkumar

India

Xingshun Qi

China

Bo Qin

China

Atoosa Rabiee

United States

Chitta Ranjan

India

Sahaj Rathi

Canada

Aathira Ravindranath

India

Ciro Romano

Italy

Farzin Roohvand

Iran (Islamic Republic of)

Mehdi Sadat

Iran (Islamic Republic of)

Ghada Salum

Egypt

Keisaku Sato

United States

Moinak Sen Sarma

India

Ke-Qing Shi

China

Hao Shi

United States

Coleman Smith

United States

Bin Song

China

Hang Sun

China

Hsin-Yun Sun

Taiwan

Sridhar Sundaram

India

Ashraf Tabll

Egypt

Tawesak Tanwandee

Thailand

Georgios Tsoulfas

Greece

Lucija Virovic-Jukic

Croatia

Benjamin l Woolbright

United States

Qiuli Xie

China

Chencheng Xie

United States

Yongning Xin

China

Weijie Xu

China

Po-Chih Yang

Taiwan

Eric M Yoshida

Canada

Yuexin Zhang

China

Rong Zhang

United States

Qingzhan Zhang

United States

Ze-Hua Zhao

China

Ming-Hua Zheng

China

Yueyong Zhu

China

Julie Zhu

Canada

 

 

 

Journal of Clinical and Translational Hepatology 2019 vol. 7, 392-393 Html ] [ PDF Full-text ]

© The Authors 2019. This article is published under the terms of the Creative Commons Attribution-Noncommercial License (CC BY-NC 4.0 ), which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non-commercial and is otherwise in compliance with the license.

 

REVIEW ARTICLE

Intensive Care Management of Acute Liver Failure: Considerations While Awaiting Liver Transplantation

Anil Seetharam*

Transplant and Advanced Liver Disease Center, University of Arizona College of Medicine, Phoenix, AZ, USA

*Correspondence to: Anil Seetharam, Banner Transplant and Advanced Liver Disease, University of Arizona College of Medicine, 441 N. 12th Street, 2nd Floor, Phoenix, AZ 85006, USA. Tel: +1-602-521-5800; Fax: +1-602-521-5337, E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Journal of Clinical and Translational Hepatology 2019;7(4):384-391 DOI: 10.14218/JCTH.2019.00032
Received: July 31, 2019 Accepted: October 27, 2019 Published online: November 13, 2019

Abstract

Acute liver failure is a unique clinical phenomenon characterized by abrupt deterioration in liver function and altered mentation. The development of high-grade encephalopathy and multisystem organ dysfunction herald poor prognosis. Etiologic-specific treatments and supportive measures are routinely employed; however, liver transplantation remains the only chance for cure in those who do not spontaneously recover. The utility of artificial and bioartificial assist therapies as supportive care—to allow time for hepatic recovery or as a bridge to liver transplantation—has been examined but studies have been small, with mixed results. Given the severity of derangements, intensive critical care is needed to successfully bridge patients to transplant, and evaluation of candidates occurs rapidly in parallel with serial reassessments of operative fitness. Psychosocial assessment is often suboptimal and relative contraindications to transplant, such as ventilator-dependence may be overlooked. While often employed to guide evaluation, no single prognostic model discriminates those who will spontaneously recover and those who will require transplant. The purpose of this review will be to summarize approaches in critical care, prognostic modeling, and medical evaluation of the acute liver failure transplant candidate.

Keywords

Acute liver failure, Thromboelastography, Intracranial hypertension, Liver assist therapy, Transplantation

 

 

 

 

Journal of Clinical and Translational Hepatology 2019 vol. 7, 384-391  [ Html ] [ PDF Full-text ]

© The Authors 2019. This article is published under the terms of the Creative Commons Attribution-Noncommercial License (CC BY-NC 4.0), which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non-commercial and is otherwise in compliance with the license.

 

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